![]() However, the role of vascular risk factors in Alzheimer’s dementia pathophysiology remains unclear. Specifically, there is ongoing debate as to whether vascular risk factors contribute to the deposition of the neuritic plaques and neurofibrillary tangles (NFTs) that represent the pathological hallmarks of Alzheimer’s dementia ( Hyman et al., 2012), lead to cerebrovascular changes that in turn lower the threshold for the clinical expression of Alzheimer’s dementia pathology, or operate through both mechanisms ( Zlokovic, 2011 Chui et al., 2012). ![]() ![]() Hypertension is among the most prevalent of these vascular risk factors, occurring in nearly one-third of adults and two-thirds of older adults worldwide ( Mills et al., 2016). Most of us take thousands of images, but tend not to do much with them. Why not create a slideshow with your pictures? PhotoStage Free Photo Slideshow makes showing off your pictures easy and fun to create, thanks to clean and intuitive interface. You begin by importing photographs and or media files by either ‘drag and drop’ method or via the file browser. ![]() Once the framework of your slideshow is in place you can add effects such as altering brightness, crop, rotate, speed, and zoom. Next, you specify what type of transitions you need fade, reveal, wipe, circle, heart, or diamond. Additionally, you can record a narration, preview the slideshow, save the current frame as an image, shuffle clips, and apply multiple clips effects such as black and white, negative, sepia, oil painting. When you have finished you can save the slideshow to disc, hardware, portable device, as an image sequence or Flash file, or if you like you can upload it, as well as create a DVD movie or data disc of your slideshow. ![]()
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